The inaugural race-meet will be held in November 2023, planned for an electric Saturday night event.
"This is an incredible moment for Formula 1 that demonstrates the huge appeal and growth of our sport with a third race in the US," said F1 CEO Stefano Domenicali.
"Las Vegas is a destination known around the world for its excitement, hospitality, thrills, and of course, the famous Strip.
“There is no better place for Formula 1 to race than in the global entertainment capital of the world and we cannot wait to be here next year.
"I want to thank everyone who helped deliver this event, especially Governor Sisolak, the Clark County Commission, Steve Hill at the [Las Vegas Convention and Visitors Authority], and our local partners.”
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