It follows the death of a 67-year-old on Monday afternoon at Kuranda Range.
The man's ute collided with a waste disposals truck around 1pm, the truck driver was taken to hospital with minor injuries.
Hours prior, an 82-year-old man from Atherton died after his Holden ute hit a car on the Knowles Road.
Forensic Crash Investigators are appealing for any witnesses to come forward for all three incidents.
It raises the total lives lost this year in the Far North to 12, police are pleading for drivers to take care over the coming holidays.
Get the latest breaking news from SCA newsrooms around Australia. Short, simple and everything you need to know.
Download LiSTNR and enjoy a new world of audio. All your favourite shows and stations in one library.